| dc.description.abstract | A comparative s1udy of Echinococcus granulosus from human and animal hosts in Kenya using isoelectric: focusing and isoenzyme analysis.
International Journal for Parasitology 12: 515-521. The soluble enzyme extracts from protoscoleces
obtained from hydatid cysts of human, camel, camel, sheep, and goat origin were compared on 1he basis
of their isoenzyme patterns for GPI and PGM using isoelectric focusing. Consistent GPI and PGM
iso~nzymc patterns were obtained for larvae of human, camel and sheep material. Cattle material varied
occasionally in having an additional ca1hodic band in some of the GPI patterns. Two distinct isoenzyme
patterns were evident in the goat material for both enzymes. The more common goat patterns were
similar 10 those of human, cattle and sheep (Kenya, U.K. and Argentina) mat~rial, which were similar rn
each other. The rare goat patterns were similar to those obtained for camel material. Cyst location in the
various intermediate hosts had no effec1 on the zymograms obtained. Additionally, no alteration in the
major banding patterns was observed between 1hc larvae and homologous adults prndu.:ed by experimcn-
1al infections. Of 26 naturally infected dogs, 19 produced adult GPI zymograms resembling human/
sheep/ goat (common form) experimental infection patterns. three were similar to experimental cattle
infections and four had camel/goat (rare form) patterns. | en_US |
