dc.contributor.author | Woday, Abay | |
dc.contributor.author | MulunehID, Muluken Dessalegn | |
dc.contributor.author | Sherif, Samiha | |
dc.date.accessioned | 2022-01-25T21:10:28Z | |
dc.date.available | 2022-01-25T21:10:28Z | |
dc.date.issued | 2019-11-11 | |
dc.identifier.citation | Woday A, Muluneh MD, Sherif S (2019) Determinants of preterm birth among mothers who gave birth at public hospitals in the Amhara region, Ethiopia: A case-control study. PLoS ONE 14(11): e0225060. https://doi.org/10.1371/journal. pone.0225060 | en_US |
dc.identifier.other | DOI: 10.1371/journal.pone.0225060 | |
dc.identifier.uri | https://repository.amref.ac.ke/handle/123456789/525 | |
dc.description | Case control study | en_US |
dc.description | Copyright: © 2019 Woday et al. This is an open
access article distributed under the terms of the
Creative Commons Attribution License, which
permits unrestricted use, distribution, and
reproduction in any medium, provided the original
author and source are credited.
Data Availability Statement: All relevant data are
within the paper and its Supporting Information
files. | en_US |
dc.description.abstract | Background
Preterm birth (PTB) is a public health issue worldwide. In developing nations, like Ethiopia,
PTB is under reported and underestimated. However, it is the leading cause of neonatal and
under-five mortality in Ethiopia. Besides, limited and non-comparative research studies to
date has been conducted in the country to address the prevalence of PTB. Therefore, this
study aims to determine predictors of PTB.
Methods
Hospital-based unmatched case control study was employed on a sample of 139 cases and
278 controls from October 2017 to December 2017 in the Amhara region, Ethiopia. The
cases and controls were proportionally allocated in each hospital based on the last one-year
case flows. As soon as a case was identified, the respective two controls were enrolled until
the required sample size was satisfied. The outcome variable was measured by using either
last menstrual period (LMP), early ultrasound result, or Ballard maturity examination. Faceto-
face interviews were conducted using a standardized, structured, and pre-tested questionnaire
to collect data. The collected data was entered into Epi-data and exported into
SPSS for analysis. Independent variables with p-values < 0.25 in the bivariate analysis were
entered into multivariable logistic regression models with forward logistic regressions
method to control the influence of covariates. Ethical clearance was ensured.
Results
A total of 134 cases and 268 controls participated with a response rate of 96.4%. After
adjusting for covariates, the following variables were associated with PTB: residing in rural
areas [AOR = 2.99: 95% CI 1.19, 7.48], low maternal age [AOR = 3.47: 95% CI 1.11, 10.83],
4.39,
24.27].
Conclusion
The study revealed maternal sociodemographic factors, short birth space, lack of antenatal
care, exposure to previous adverse birth outcomes and facing medical illnesses during
pregnancy were the predictors of PTB. Therefore, inclusive preventive and control interventions
should be developed at regional, zonal and district levels to reduce the burden of PTB
among women resided in rural areas such as integrating antenatal care services into the
existing health extension packages. Study results suggest increasing the awareness of
PTB, contraceptive utilization and counseling to enhance birth spacing, antenatal care visits,
and accessibility to services among women in Ethiopia should be given due attention. Health
care providers should focus on mothers with previous adverse birth outcomes and those
exposed to medical problems during pregnancy. Additional community based longitudinal
studies supplemented with qualitative methods are recommended. | en_US |
dc.language.iso | en | en_US |
dc.publisher | ResearchGate | en_US |
dc.subject | Preterm birth (PTB) | en_US |
dc.subject | Neonatal and under-five mortality | en_US |
dc.subject | Last menstrual period (LMP) | en_US |
dc.subject | Ballard maturity examination | en_US |
dc.title | Determinants of Preterm Birth Among Mothers who Gave Birth at Public Hospitals in the Amhara Region, Ethiopia A Case-Control Study | en_US |
dc.type | Article, Journal | en_US |