Browsing by Subject "Parasitaemia"

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Chlorproguanil/Dapsone for the Treatment of Non-severe Plasmodium Falciparum Malaria in Kenya: a pilot study

Watkins, W.M.; Brandling-Bennett, A.D.; Nevill, C.G.; Carter, J.Y.; Boriga, D.A.; Howells, R.E.; Koech, D.K. (Oxford University Press, 5/1/1988)

Chlorocycloguanil, the active metabolite of chlorproguanil, was synergistic in vitro with dapsone against 2 culture-adapted Plasmodium falciparum isolates from Kenya; maximal synergy occurred at lower concentrations that ...
A Single Dose of Intramuscular Sulfadoxine-Pyrimethamine as an Adjunct to Quinine in the Treatment of Severe Malaria: Pharmacokinetics and Efficacy

Newton, C. R. J. C.; Winstanley, P. A.; Watkins, W. M.; Mwangi, I. N.; Waruiru, C. M.; Mberu, E. K.; Warn, P. A.; Nevill, C.G.; Marsh, K. (Oxford University Press, 4/1/1983)

It has been suggested that sulfadoxine-pyrimethamine (SDPM) may be useful in the treatment of severe malaria since it could enhance the killing of parasites by quinine (QN) and it can be given as a single intramuscular ...