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Cytokines and Onchocerciasis-Associated Epilepsy, a Pilot Study and Review of the Literature
(MDPI, 3/7/2021)
Neuro-inflammation may be associated with onchocerciasis-associated epilepsy (OAE) but thus far very few immunological studies have been performed in children with this form of epilepsy. In a pilot study we measured the ...
High Prevalence of Epilepsy in an Onchocerciasis-Endemic Area in Mvolo County, South Sudan: A Door-To-Door Survey
(MDPI, 5/14/2021)
In June 2020, a door-to-door household survey was conducted in Mvolo County, an onchocerciasis-endemic area in South Sudan. A total of 2357 households containing 15,699 individuals agreed to participate in the study. Of ...
“Slash and Clear”, a Community-Based Vector Control Method to Reduce Onchocerciasis Transmission by Simulium sirbanum in Maridi, South Sudan: A Prospective Study
(Pathogens, 2021-10-15)
Abstract: Background: High ongoing Onchocerca volvulus transmission was recently documented in
Maridi County, South Sudan. To complement community-directed treatment with ivermectin (CDTI)
as the main onchocerciasis ...
Effect of Ivermectin Treatment on the Frequency of Seizures in Persons with Epilepsy Infected with Onchocerca volvulus
(MDPI, 2020-12-31)
A clinical trial performed in the Democratic Republic of Congo (DRC), among persons with
epilepsy (PWE) infected with Onchocerca volvulus treated with anti-seizure medication suggested that
ivermectin reduces the seizure ...
Epilepsy-related Stigma and Cost in Two Onchocerciasis-endemic Areas in South Sudan: A Pilot Descriptive Study
(Elsevier, 2020-08-06)
Introduction: Epilepsy is a major public health concern in sub-Saharan Africa, particularly in resource-limited rural villages where persons with epilepsy (PWE) are often confronted with a wide treatment gap, frequent ...
Ivermectin Treatment Response in Onchocerca Volvulus Infected Persons with Epilepsy: A Three-Country Short Cohort Study
(MDPI, 2020-07-29)
Despite a long history of community-directed treatment with ivermectin (CDTI), a high ongoing Onchocerca volvulus transmission is observed in certain onchocerciasis-endemic regions in Africa with a high prevalence of ...
Persons with Onchocerciasis-associated Epilepsy and Nodding Seizures Have a More Severe Form of Epilepsy with More Cognitive Impairment and Higher Levels of Onchocerca volvulus Infection
(Epileptic Disorders, 2020-06)
Aims. Following previous reports of very high epilepsy
prevalence in the onchocerciasis-endemic villages in Maridi County, South
Sudan, a study was conducted to investigate the association between the
level of Onchocerca ...