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Variability in the Metabolism of Proguanil to the Active Metabolite Cycloguanil in Healthy Kenyan Adults
(Oxford University Press, 1990-08-01)
Extensive metabolizers (EM) and poor metabolizers (PM) of the malaria chemoprophylactic drug proguanil have been identified by measuring the proguanil/cycloguanil ratio in urine following a single dose of the pro-drug. The ...
Chapter 1: Barriers to Behaviour Change as a Response to STD Including HIV/AIDS: The East African Experience
(Resistances to Behavioural Change to Reduce HIV/AIDS Infection, 1999)
This chapter is based on a regional project being implemented in Uganda, Kenya, Tanzania and Ethiopia by the African Medical Research Foundation. The project, which targets young people aged 10-25 years, is a five-year ...