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    Mathematical Modelling of COVID-19 Transmission in Kenya: A Model with Reinfection Transmission Mechanism

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    Publication Date
    2021-10-16
    Author
    Kimathi, George
    Type
    Article, Journal
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    Citation

    Wangari IM, Sewe S, Kimathi G, Wainaina M, Kitetu V, Kaluki W. Mathematical Modelling of COVID-19 Transmission in Kenya: A Model with Reinfection Transmission Mechanism. Comput Math Methods Med. 2021 Oct 16;2021:5384481. doi: 10.1155/2021/5384481. Erratum in: Comput Math Methods Med. 2025 Sep 26;2025:9781759. doi: 10.1155/cmmm/9781759. PMID: 34777563; PMCID: PMC8578696.

    Abstract/Overview

    In this study we propose a Coronavirus Disease 2019 (COVID-19) mathematical model that stratifies infectious subpopulations into: infectious asymptomatic individuals, symptomatic infectious individuals who manifest mild symptoms and symptomatic individuals with severe symptoms. In light of the recent revelation that reinfection by COVID-19 is possible, the proposed model attempt to investigate how reinfection with COVID-19 will alter the future dynamics of the recent unfolding pandemic. Fitting the mathematical model on the Kenya COVID-19 dataset, model parameter values were obtained and used to conduct numerical simulations. Numerical results suggest that reinfection of recovered individuals who have lost their protective immunity will create a large pool of asymptomatic infectious individuals which will ultimately increase symptomatic individuals with mild symptoms and symptomatic individuals with severe symptoms (critically ill) needing urgent medical attention. The model suggests that reinfection with COVID-19 will lead to an increase in cumulative reported deaths. Comparison of the impact of non pharmaceutical interventions on curbing COVID19 proliferation suggests that wearing face masks profoundly reduce COVID-19 prevalence than maintaining social/physical distance. Further, numerical findings reveal that increasing detection rate of asymptomatic cases via contact tracing, testing and isolating them can drastically reduce COVID-19 surge, in particular individuals who are critically ill and require admission into intensive care.

    Subject/Keywords
    Mathematical Modelling, COVID-19 Transmission, Kenya, Transmission Mechanism
    Publisher
    Comput Math Methods Med
    Permalink
    https://repository.amref.ac.ke/handle/20.500.14173/1104
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