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    Clinical features, immunological interactions and household determinants of visceral leishmaniasis and malaria coinfections in West Pokot, Kenya: protocol for an observational study

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    doi.org/10.1136/bmjopen-2022-068679 (613.9Kb)
    Publication Date
    2023-04-17
    Authors
    Dijk, Norbert
    Carter, Jane
    Omondi, Wyckliff
    Type
    Article, Journal
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    Citation

    van Dijk N, Carter J, Omondi W, Mens P, Schallig H. Clinical features, immunological interactions and household determinants of visceral leishmaniasis and malaria coinfections in West Pokot, Kenya: protocol for an observational study. BMJ Open. 2023 Apr 17;13(4):e068679. doi: 10.1136/bmjopen-2022-068679. PMID: 37068901; PMCID: PMC10111886.

    Abstract/Overview

    Introduction Visceral leishmaniasis (VL) and malaria are two deadly parasitic diseases that coexist in West Pokot County, Kenya. The local population is at considerable risk of coinfection with VL and malaria; however, few studies have described the clinical implications of this comorbidity. Questions remain regarding the immune responses responsible for possible predisposing or protective effects. Moreover, characterisation of environmental and household risk factors for co-acquiring VL and malaria is warranted to increase awareness and guide implementation of targeted control strategies. This protocol intends to address these knowledge gaps concerning VL–malaria coinfections.

    Subject/Keywords
    Epidemiology; Immunology; MICROBIOLOGY; PARASITOLOGY.
    Further Details

    DOI: 10.1136/bmjopen-2022-068679

    Publisher
    BMJ Open
    Permalink
    https://repository.amref.ac.ke/handle/20.500.14173/987
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    • Peer-Reviewed Articles [29]

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